Abstract Title:

Concentration of NK cells afterβ-glucan and vitamin D supplementation in patients with diabetic retinopathy.

Abstract Source:

Folia Microbiol (Praha). 2020 Apr 4. Epub 2020 Apr 4. PMID: 32248405

Abstract Author(s):

Richter Josef, Pohorska Jitka, Závorková Martina, Král Vlastimil, Stiborova Ivana, Dobiasova Rajnohova Lucie, Vetvicka Vaclav

Article Affiliation:

Richter Josef


In our study, we focused on possible effects of supplementation with glucan and vitamin D on total numbers of NK cells in patients with diabetic retinopathy. We evaluated possible relations among nutritional state (BMI), leptin levels, and total numbers of NK cells in patients supplemented with (1) glucan and vitamin D, (2) vitamin D and placebo, and (3) vitamin D alone. Our results show that 3 months of supplementation with both glucan and vitamin D resulted in significant improvements of NK cell numbers. In addition, we found statistically significant correlation between NK cell numbers and leptin levels. Based on these results, we propose that the molecule responsible for these changes is glucan, as vitamin D alone or together with placebo caused no effects.

Study Type : Human Study

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