Biosynthesis of silver nanoparticles using the extract of Alternanthera sessilis-antiproliferative effect against prostate cancer cells.
Cancer Nanotechnol. 2013;4(6):137-143. Epub 2013 Sep 15. PMID: 26069509
M Jannathul Firdhouse
Green synthesis of silver nanoparticles was carried out using the aqueous extract of Alternanthera sessilis under various experimental conditions. The aqueous extract of Alternanthera sessilis showed significant potential for the quick reduction of silver ions. The synthesized silver nanoparticles were characterized with UV-visible absorption spectrophotometer, XRD, SEM, and FTIR analysis. The average crystallite size as calculated from x-ray diffraction studies and SEM analysis was found to be less than 100 nm. The cytotoxic activity of synthesized nanosilver was carried out against prostate cancer cells (PC3) by MTT assay and found to show significant activity. The present work of biosynthesis of silver nanoparticles using Alternanthera sessilis appears to be cost effective, eco-friendly, and an alternative to conventional method of synthesis.