Both preclinical and clinical data available in the literature show that Vitamin C plays a pivotal role in a number of processes involved in the pathogenesis of CVD. - GreenMedInfo Summary

The potential beneficial effects of the antioxidant properties of vitamin C have been investigated in a number of pathological conditions. In this review, we assess both clinical and preclinical studies evaluating the role of vitamin C in cardiac and vascular disorders, including coronary heart disease, heart failure, hypertension, and cerebrovascular diseases. Pitfalls and controversies in investigations on vitamin C and cardiovascular disorders are also discussed.