Article Publish Status: FREE
Abstract Title:

Altered cortical activation from the hand after facial botulinum toxin treatment.

Abstract Source:

Ann Clin Transl Neurol. 2014 Jan ;1(1):64-8. Epub 2013 Nov 25. PMID: 25356383

Abstract Author(s):

Sara Haenzi, Gabor Stefanics, Tatjana Lanaras, Maurizio Calcagni, Arko Ghosh

Article Affiliation:

Sara Haenzi


Plastic interactions between face and hand cortical tactile circuits occur after severe injuries that affect the hand such as in amputation or spinal cord injury. However, whether loss of facial movements alters the cortical circuits involved in processing tactile inputs from the hand remains unknown. In this prospective observational study we used electroencephalography (EEG) to measure cortical activity evoked by tactile stimulation of the hands before and after botulinum toxin-A-induced facial paralysis. We found a reduction in the tactile event-related potentials (ERPs) 6 weeks after the treatment. This suggests that the limited paralysis of facial muscles induced during cosmetic interventions designed to smooth lines and wrinkles on the face is sufficient to alter the cortical processing of tactile inputs from the hand.

Study Type : Human Study
Additional Links
Problem Substances : Botox : CK(20) : AC(1)

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