Abstract Title:

Benefits of the consumption of Brazil nut () extract in male reproductive parameters of streptozotocin-induced diabetic rats.

Abstract Source:

J Diabetes Metab Disord. 2020 Jun ;19(1):187-196. Epub 2020 Feb 5. PMID: 32550168

Abstract Author(s):

Leonardo Parreira Silva Nascimento, Vanessa Cardoso Pires, Daniel Araki Ribeiro, Andréa Pittelli Boiago Gollücke, Hirochi Yamamura, Odair Aguiar Junior

Article Affiliation:

Leonardo Parreira Silva Nascimento


Objective: The objective of this study was to evaluate the effects of intake of Brazil nut extract (BN) or sodium selenite solution on reproductive parameters of male diabetic animals.

Methods: A total of 48 Wistar rats were distributed into six groups: diabetes ( = 8); diabetes and Brazil nut extract ( = 8); diabetes and sodium selenite (NaSeO) ( = 8); Brazil nut extract (n = 8); sodium selenite (n = 8) and control (n = 8). A single dose of streptozotocin (65 mg/kg) was injected intravenously to the rats to induce diabetes. BN or NaSeOwere administered by gavage for 56 days.

Results: The diabetes caused critical alterations on body mass gain, reproductive parameters and antioxidant capacity. Treatments with both BN or NaSeOwere able to increase significantly the glutathione peroxidase and the daily sperm production, both in diabetic ( < 0.01 and < 0.05) and in healthy animals (p < 0.01 and p < 0.05).

Conclusion: The Brazil nut extract and sodium selenite were able to improve some reproductive parameters of diabetic rats. Moreover, we could infer that this effect is probably due to the natural selenium content of the BN.

Study Type : Animal Study

Print Options

Key Research Topics

Sayer Ji
Founder of GreenMedInfo.com

Subscribe to our informative Newsletter & get Nature's Evidence-Based Pharmacy

Our newsletter serves 500,000 with essential news, research & healthy tips, daily.

Download Now

500+ pages of Natural Medicine Alternatives and Information.

This website is for information purposes only. By providing the information contained herein we are not diagnosing, treating, curing, mitigating, or preventing any type of disease or medical condition. Before beginning any type of natural, integrative or conventional treatment regimen, it is advisable to seek the advice of a licensed healthcare professional.

© Copyright 2008-2022 GreenMedInfo.com, Journal Articles copyright of original owners, MeSH copyright NLM.