Article Publish Status: FREE
Abstract Title:

Can Zn Be a Critical Element in COVID-19 Treatment?

Abstract Source:

Biol Trace Elem Res. 2020 May 26. Epub 2020 May 26. PMID: 32458149

Abstract Author(s):

Mohammad Tariqur Rahman, Syed Zahir Idid

Article Affiliation:

Mohammad Tariqur Rahman


The current COVID-19 pandemic caused by SARS-CoV-2 has prompted investigators worldwide to search for an effective anti-viral treatment. A number of anti-viral drugs such as ribavirin, remdesivir, lopinavir/ritonavir, antibiotics such as azithromycin and doxycycline, and anti-parasite such as ivermectin have been recommended for COVID-19 treatment. In addition, sufficient pre-clinical rationale and evidence have been presented to use chloroquine for the treatment of COVID-19. Furthermore, Zn has the ability to enhance innate and adaptive immunity in the course of a viral infection. Besides, Zn supplement can favour COVID-19 treatment using those suggested and/or recommended drugs. Again, the effectiveness of Zn can be enhanced by using chloroquine as an ionophore while Zn inside the infected cell can stop SARS-CoV-2 replication. Given those benefits, this perspective paper describes how and why Zn could be given due consideration as a complement to the prescribed treatment of COVID-19.

Study Type : Review
Additional Links
Pharmacological Actions : Antiviral Agents : CK(1307) : AC(596)

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