Article Publish Status: FREE
Abstract Title:

How do vegetable oils (hazelnut and canola) affect the reproductive system in male rats?

Abstract Source:

Arch Ital Urol Androl. 2018 Mar 31 ;90(1):54-58. Epub 2018 Mar 31. PMID: 29633799

Abstract Author(s):

Bűlent Kati, Fatih Oguz, Ismet Yilmaz, Ender Akdemir, Ramazan Altintas, Nusret Akpolat, Mehmet Cagatay Taskapan

Article Affiliation:

Bűlent Kati


OBJECTIVE: Vegetable oils have an important place in our daily diet. This study starts from this point to investigate the effects of canola oil and hazelnut oil in the male reproductive system in rats.

MATERIAL AND METHODS: 30 male rats were used in this 16-week study. The animals were divided into three groups: the animals in group I served as the control group, while the animals in group II and group III were fed with hazelnut and canola oil, respectively. The testes of all rats were excised for histopathologic evaluation and immunohistochemical (IHC) evaluation with a standard method. Blood samples were obtained for determination of serum hormone levels.

RESULTS: No significant differences were noted with respect to behavior or weight among the three groups. Rats in the canola oil group (group III) had higher luteinizing hormone (LH) and higher testosterone levels than rats in the control group. Rats who received hazelnut oil (group II) exhibited similar findings, with these levels being higher than they were in the control group. No statistical differences were shown for histopathology or IHC testosterone antibody levels across all treatment groups. Conclussion: Canola oil was shown to have a greater effect on serum LH and testosterone compared to the control group and the group fed with hazelnut oil. Further investigation is required into how these oils affect serum hormone and sperm activity.

Study Type : Animal Study
Additional Links
Problem Substances : Canola Oil : CK(2) : AC(1)

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