Abstract Title:

Cardiovascular Modulating Effects of Magnolol and Honokiol, two polyphenolic compounds from Traditional Chinese Medicine-Magnolia officinalis.

Abstract Source:

Curr Drug Targets. 2019 Oct 24. Epub 2019 Oct 24. PMID: 31749425

Abstract Author(s):

Yuan Yuan, Xiaocui Zhou, Yuanyuan Wang, Yan Wang, Xiangyan Teng, Shuaiyu Wang

Article Affiliation:

Yuan Yuan


Honokiol and its isomer magnolol are poly-phenolic compounds isolated from the Magnolia officinalis that exert cardiovascular modulating effects via a variety of mechanisms. They are used as a blood-quickening and stasis-dispelling agents in Traditional Chinese Medicine and confirmed to have therapeutic potential in atherosclerosis, thrombosis, hypertension, and cardiac hypertrophy. This comprehensive review summarizes the current date regarding the cardioprotective mechanisms of those compounds and identifies areas for further research.

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