Article Publish Status: FREE
Abstract Title:

Cardiovascular Risk of Proton Pump Inhibitors.

Abstract Source:

Methodist Debakey Cardiovasc J. 2019 Jul-Sep;15(3):214-219. PMID: 31687101

Abstract Author(s):

Hannah Ariel, John P Cooke

Article Affiliation:

Hannah Ariel


Proton pump inhibitors (PPIs) are effective agents for the treatment of gastroesophageal reflux (GERD). However, these drugs have not been approved for long-term use. Now sold over the counter, these agents are being used chronically for GERD without medical supervision. The long-term use of PPIs may have significant adverse effects, in part mediated by their effect of accelerating vascular aging. Physicians should assist patients in tapering off their use of PPIs and replacing them with lifestyle modifications and/or other agents that have better long-term safety profiles.

Study Type : Review
Additional Links
Adverse Pharmacological Actions : Cardiotoxic : CK(1000) : AC(164)

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