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Abstract Title:

Optic neuritis after influenza vaccination.

Abstract Source:

Am J Ophthalmol. 1997 Nov ;124(5):703-4. PMID: 9372734

Abstract Author(s):

T P Hull, J H Bates

Article Affiliation:

T P Hull

Abstract:

PURPOSE: To present evidence for a causal relation between optic neuritis and influenza vaccination.

METHODS: Case report. In a 59-year-old woman with bilateral optic neuritis, neuro-ophthalmologic examination, magnetic resonance imaging, fluorescent treponemal antibody absorption test, antinuclear antibodies, and complete blood cell count and chemistry were performed.

RESULTS: Our patient developed bilateral optic neuritis on two occasions, 1 year apart. No evidence of neuroretinitis, syphilis, or systemic lupus erythematosus was identified. Influenza vaccination was given 2 weeks before the onset of each episode.

CONCLUSION: This case provides compelling clinical evidence that implicates influenza vaccination as a cause of optic neuritis.

Study Type : Human: Case Report

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