n/a
Abstract Title:

Postvaccinal parkinsonism.

Abstract Source:

Mov Disord. 1992 ;7(2):178-80. PMID: 1350062

Abstract Author(s):

R S Alves, E R Barbosa, M Scaff

Article Affiliation:

R S Alves

Abstract:

A 5-year-old boy, with a history of fever beginning 15 days after a vaccination for measles, developed a rigid-akinetic syndrome 3 days after the fever began. A spinal tap obtained 1 week after the onset of fever showed pleocytosis with a monocellular pattern. A CT scan of the head and EEG did not disclose any abnormality. An MRI performed 3 months after the event, however, showed clear-cut evidence of bilateral substantia nigra lesions, suggesting secondary gliosis. The response to levodopa was good, but adverse reactions appeared early. The child is now 7 years old. Bromocriptine, deprenyl, and levodopa have produced a remarkable improvement of the parkinsonian features.

Study Type : Human: Case Report

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