Abstract Title:

[Vitamin B6 deficiency caused by the use of levodopa].

Abstract Source:

Ned Tijdschr Geneeskd. 2018 08 23 ;162. Epub 2018 Aug 23. PMID: 30212001

Abstract Author(s):

Wouter van der Steen, Tom den Heijer, Joost Groen

Article Affiliation:

Wouter van der Steen


BACKGROUND: There are indications that the use of levodopa/carbidopa can cause symptomatic vitamin B6 deficiency. However, this has only been described for patients who used the product in the form of an intestinal gel.

CASE DESCRIPTION: We are describing 3 patients who developed vitamin B6 deficiency while using levodopa/carbidopa in tablet form. All 3 patients developed symptoms consistent with peripheral axonal polyneuropathy.

CONCLUSION: The cases of our patients are providing support for the idea that oral use of levodopa/carbidopa can cause symptomatic vitamin B6 deficiency.

Study Type : Human: Case Report
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