Abstract Title:

Case report: cefazolin-induced hemolytic anemia.

Abstract Source:

Clin Orthop Relat Res. 2007 Jun;459:260-2. PMID: 17308481

Abstract Author(s):

Douglas L Cerynik, Gwo-Chin Lee, Reginald Fayssoux, Nirav H Amin

Article Affiliation:

Department of Orthopaedic Surgery, Hahnemann University Hospital, Philadelphia, PA 19102, USA.


Antibiotic-induced hemolytic anemia is a rare complication. Prophylactic cephalosporins are widely used in patients having orthopaedic procedures. When there is a precipitous drop in hemoglobin levels, it is important for the clinician to consider the possibility of drug-induced anemia when other causes of blood loss have been excluded. We present a patient with no prior drug allergies who had antibiotic-induced hemolytic anemia develop after total knee arthroplasty.

Study Type : Human: Case Report
Additional Links
Problem Substances : Cefazolin : CK(6) : AC(2)
Adverse Pharmacological Actions : Hemolytic : CK(20) : AC(6)

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