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Article Publish Status: FREE
Abstract Title:

and Its Metabolite Asiatic Acid: Wound Healing Effects and Therapeutic Potential.

Abstract Source:

Metabolites. 2023 Feb 14 ;13(2). Epub 2023 Feb 14. PMID: 36837896

Abstract Author(s):

Lúcio Ricardo Leite Diniz, Leonardo Luiz Calado, Allana Brunna Sucupira Duarte, Damião Pergentino de Sousa

Article Affiliation:

Lúcio Ricardo Leite Diniz

Abstract:

An intense effort has been focused on new therapeutic approaches and the development of technologies for more efficient and rapid wound healing. The research for plants used for long time in traditional medicine in the treatment of wound has become a promising strategy to obtain drugs therapeutically useful in the acute and chronic wound management. In this context,(Apiaceae) has been used to treat a variety of skin diseases, such as leprosy, lupus, varicose ulcers, eczema and psoriasis, in Asiatic traditional medicine for thousands of years. Studies have shown thatextracts (CAE) display activity in tissue regeneration, cell migration and wound repair process by promoting fibroblast proliferation and collagen synthesis. Preliminary findings have shown that the asiatic acid is one of the main active constituents of, directly associated with its healing activity. Thus, this study discusses aspects of the effects ofand its active component, asiatic acid, in different stages of the healing process of cutaneous wounds, including phytochemical and antimicrobial aspects that contribute to its therapeutic potential.

Study Type : Review

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