Article Publish Status: FREE
Abstract Title:

andAnti-Activities ofLeaf Extract.

Abstract Source:

Prev Nutr Food Sci. 2016 Sep ;21(3):197-201. Epub 2016 Sep 30. PMID: 27752495

Abstract Author(s):

Hong-Mei Zheng, Myung-Joo Choi, Jae Min Kim, Kye Wan Lee, Yu Hwa Park, Don Haeng Lee

Article Affiliation:

Hong-Mei Zheng


infection is associated with an increased risk of developing upper gastrointestinal tract diseases. However, treatment failure is a major cause of concern mainly due to possible recurrence of infection, the side effects, and resistance to antibiotics. The aim of this study was to investigate the activities ofleaf extract (CAE) againstbothand. The minimum inhibitory concentrations (MICs) against 55 clinically isolated strains ofwere tested using an agar dilution method. The MICs of CAE ranged from 0.125 mg/mL to 8 mg/mL, effectiveness in inhibitinggrowth was 2 mg/mL. The anti-effects of CAEwere also examined in-infected C57BL/6 mice. CAE was orally administrated once daily for 3 weeks at doses of 50 mg/kg and 250 mg/kg. CAE at the 50 mg/kg dose significantly reducedcolonization in mice gastric mucosa. Our study provides novel insights into the therapeutic effects of CAE againstinfection, and it suggests that CAE may be useful as an alternative therapy.

Study Type : Animal Study, In Vitro Study

Print Options

Key Research Topics

Sayer Ji
Founder of GreenMedInfo.com

Subscribe to our informative Newsletter & get Nature's Evidence-Based Pharmacy

Our newsletter serves 500,000 with essential news, research & healthy tips, daily.

Download Now

500+ pages of Natural Medicine Alternatives and Information.

This website is for information purposes only. By providing the information contained herein we are not diagnosing, treating, curing, mitigating, or preventing any type of disease or medical condition. Before beginning any type of natural, integrative or conventional treatment regimen, it is advisable to seek the advice of a licensed healthcare professional.

© Copyright 2008-2021 GreenMedInfo.com, Journal Articles copyright of original owners, MeSH copyright NLM.