Abstract Title:

Efficacy and safety of topical Matricaria chamomilla L. (chamomile) oil for knee osteoarthritis: A randomized controlled clinical trial.

Abstract Source:

Complement Ther Clin Pract. 2015 Aug ;21(3):181-7. Epub 2015 Jun 9. PMID: 26256137

Abstract Author(s):

Ruhollah Shoara, Mohammad Hashem Hashempur, Alireza Ashraf, Alireza Salehi, Shadab Dehshahri, Zahra Habibagahi

Article Affiliation:

Ruhollah Shoara


OBJECTIVE: To assess the efficacy and safety of topical Matricaria chamomilla (Chamomile) oil in patients with knee osteoarthritis.

METHOD: Patients were randomized and treated with topical chamomile oil, diclofenac or placebo, 3 times/day for 3 weeks. They were allowed to use acetaminophen as analgesic. The patients were asked about their total acetaminophen use. Moreover, they were assessed in the terms of pain, physical function and stiffness by using Western Ontario and McMaster Universities Osteoarthritis Index (WOMAC) questionnaire at the enrolling and weekly.

RESULTS: Chamomile oil significantly reduced the patients' need for acetaminophen (P = 0.001) compared with diclofenac and placebo. However, there were no significant differences in WOMAC questionnaire domains. The patients did not report any adverse events by using chamomile oil.

CONCLUSION: Chamomile oil decreased the analgesic demand of patients with knee osteoarthritis. In addition, it may show some beneficial effects on physical function, and stiffness of the patients.

Study Type : Human Study

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Sayer Ji
Founder of GreenMedInfo.com

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