Abstract Title:

The oral health needs of children after treatment for a solid tumour or lymphoma.

Abstract Source:

Int J Paediatr Dent. 2010 Jan;20(1):15-23. PMID: 20059589

Abstract Author(s):

Alison Hutton, Moira Bradwell, Martin English, Iain Chapple

Article Affiliation:

Dental Specialties Department, Birmingham Children's Hospital, Birmingham UK. [email protected]


BACKGROUND: With increasing survival rates for childhood cancer, late effects are of growing importance. Oral health is central to general health, level of nutrition, quality of life, and is significant in the holistic care of children during cancer therapy. HYPOTHESIS: The oral health needs of children treated for solid tumours/lymphoma will be greater than the general population, groups will differ according to tumour and treatment. DESIGN: One hundred and twenty patients, 0-17 years, under follow-up from 01/07/06 to 07/02/07 were investigated for caries, opacities, microdontia, and gingivitis. Analysis was performed with stratification according to tumour and treatment. Comparisons made with the UK 2003 Child Dental Health Survey. RESULTS: The neuroblastoma group and high-dose chemotherapy with stem-cell rescue (HDCSCR) therapy group had increased caries of the primary teeth. Chi-squared analysis revealed a statistically significant relationship (P<0.03) between the age at receipt of chemotherapy (<3.5 years) and the presence of microdont teeth. CONCLUSION: Oral health care is important for all patients particularly those with a neuroblastoma, or who received HDCSCR. Patients should be advised about the possibility of microdontia in the permanent dentition following chemotherapy under 3.5 years.

Study Type : Human Study

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