Article Publish Status: FREE
Abstract Title:

Effect of High-Intensity Interval Training Combined with L-Citrulline Supplementation on Functional Capacities and Muscle Function in Dynapenic-Obese Older Adults.

Abstract Source:

J Clin Med. 2018 Dec 17 ;7(12). Epub 2018 Dec 17. PMID: 30562948

Abstract Author(s):

Fanny Buckinx, Gilles Gouspillou, Livia P Carvalho, Vincent Marcangeli, Guy El Hajj Boutros, Maude Dulac, Philippe Noirez, José A Morais, Pierette Gaudreau, Mylène Aubertin-Leheudre

Article Affiliation:

Fanny Buckinx


BACKGROUND: To compare the effects of high-intensity interval training (HIIT) alone vs. HIIT combined with L-citrulline (CIT) supplementation on functional capacity and muscle function in dynapenic-obese elderly.

METHODS: A total of 56 obese (fat mass: men>25%, women>35%) and dynapenic (grip strength/body weight: women<0.44, men<0.61) subjects were recruited and divided in two groups: HIIT+CIT (= 26; age: 6 5± four years) vs. HIIT+Placebo (PLA,= 30; age: 68± four years). Participants followed a 12-week HIIT using an elliptical trainer. Participants took a single and isocaloric 10 g-dose of CIT or PLA every day. Body composition; functional and aerobic capacities; absolute or relative upper and lower limbs muscle strength, muscle power; and energy balance were measured pre and post intervention.

RESULTS: Both groups significantly improved functional capacity and muscle function. However, HIIT+CIT demonstrated greater improvements in fast-paced Timed Up& Go (= 0.04) and upper limbs muscle strength (absolute and relative) (= 0.05) than HIIT+Placebo.

CONCLUSION: CIT supplementation when combined with HIIT seems to induce greater improvements in upper limbs muscle strength and walking speed in dynapenic-obese elderly. Further studies are needed to confirm our results, to elucidate the mechanisms underlying the beneficial effects of CIT and to define the long-term impact of CIT/HIIT.

Study Type : Human Study
Additional Links

Print Options

Key Research Topics

Sayer Ji
Founder of GreenMedInfo.com

Subscribe to our informative Newsletter & get Nature's Evidence-Based Pharmacy

Our newsletter serves 500,000 with essential news, research & healthy tips, daily.

Download Now

500+ pages of Natural Medicine Alternatives and Information.

This website is for information purposes only. By providing the information contained herein we are not diagnosing, treating, curing, mitigating, or preventing any type of disease or medical condition. Before beginning any type of natural, integrative or conventional treatment regimen, it is advisable to seek the advice of a licensed healthcare professional.

© Copyright 2008-2022 GreenMedInfo.com, Journal Articles copyright of original owners, MeSH copyright NLM.