Clindamycin-resistant group B Streptococcus and failure of intrapartum prophylaxis to prevent early-onset disease.
J Pediatr. 2010 Mar;156(3):501-3. Epub 2010 Jan 13. PMID: 20056242
Division of Pediatric Infectious Diseases, Department of Pediatrics, University of Utah School of Medicine, Salt Lake City, UT, USA. email@example.com
Guidelines recommend intrapartum antibiotic prophylaxis (IAP) for parturient women who have a screen positive for group B Streptococcus (GBS). Clindamycin should be used for IAP only if the maternal GBS isolate is susceptible. We report a case of clindamycin-resistant GBS disease in a newborn infant whose mother received clindamycin IAP, and we review clindamycin susceptibility testing.