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Article Publish Status: FREE
Abstract Title:

Coconut Shell Liquid Smoke Promotes Burn Wound Healing.

Abstract Source:

J Evid Based Complementary Altern Med. 2016 Nov 6. Epub 2016 Nov 6. PMID: 27821610

Abstract Author(s):

Vita Murniati Tarawan, Kemala Isnainiasih Mantilidewi, Ika Miqra Dhini, Putri Teesa Radhiyanti, Endang Sutedja

Article Affiliation:

Vita Murniati Tarawan

Abstract:

The aim of this study was to evaluate burn wound healing activity of coconut shell liquid smoke (CS-LS) in a burn wound animal model. Burn wound-induced mice were treated with CS-LS (CS-LS group), povidone iodine 10% (povidone group), or NaCl 0.9% (NaCl group). Application of CS-LS promoted wound contraction compared to that of the povidone and NaCl groups (P<.05). This study showed a positive correlation between the number of fibroblasts and wound contraction. The number of fibroblasts was highest in the CS-LS group, compared to that of the povidone and NaCl groups (P<.05). In conclusion, CS-LS promotes burn wound healing by one possible mechanism, by increasing the number of fibroblasts. The results indicate that further experimental trials are needed to develop CS-LS as an alternative topical drug for burn wound healing.

Study Type : Animal Study

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Sayer Ji
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