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Article Publish Status: FREE
Abstract Title:

Combination of vegetable soup and glucan demonstrates synergistic effects on macrophage-mediated immune responses.

Abstract Source:

Food Sci Biotechnol. 2021 Apr ;30(4):583-588. Epub 2021 Mar 13. PMID: 33936850

Abstract Author(s):

Ha-Nul Lee, Joo-Hee Choi, Ji-Yeon Park, Jae-Hun Ahn, Da Eun Jang, Jae Gun Shim, Jong-Hwan Park, Young-Min Kim

Article Affiliation:

Ha-Nul Lee

Abstract:

: Vegetable soup (VS), a plant-based functional food, has been used as a traditional folk medicine and is attracting attention for its ability to enhance the immune response.β-Glucan, a well-established and effective immunomodulator, has synergistic effects when used in combination with some bioactive compounds. In the present study, we aimed to evaluate the synergistic immunomodulatory effects of the combination of VS and β-glucan on macrophage-mediated immune responses. β-Glucan was demonstrated to synergistically enhance the VS-stimulated immune response, including the production of interleukin-6, tumor necrosis factor-α, and nitric oxide, mainly through the mitogen-activated protein kinase pathway in macrophages. In addition, this combination has the potential for further development in functional foods with immune-enhancing activity.

Supplementary Information: The online version contains supplementary material available at 10.1007/s10068-021-00888-x.

Study Type : In Vitro Study

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