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Abstract Title:

Effects of electroacupuncture on dry eye: A pilot randomized controlled trial.

Abstract Source:

Acta Ophthalmol. 2022 Oct 17. Epub 2022 Oct 17. PMID: 36245315

Abstract Author(s):

Guang Yang, Xiehe Kong, Xiaocong Guo, Yanting Yang, Chen Xie, Yunqiong Lu, Jie Liu, Huangan Wu, Dan Zhang, Yuelan Zou, Cuihong Zhang, Jue Hong, Xiaopeng Ma

Article Affiliation:

Guang Yang

Abstract:

PURPOSE: The purpose of the study was to assess the efficacy of electroacupuncture on dry eye (DE).

METHODS: Eighty-four DE patients were randomly assigned to receive electroacupuncture (EAG) three times a week or 0.1% sodium hyaluronate artificial tears (ATG) four times per day for 4 weeks. The primary outcomes were non-invasive tear film breakup time (NIBUT) and tear meniscus height (TMH). The secondary outcomes included the ocular surface disease index (OSDI), Schirmer I test (SIT), corneal sodium fluorescein staining (CFS) score, corneal topography descriptors surface asymmetry index (SAI) and surface regularity index (SRI), corneal sensitivity, 36-item Short-form Health Survey (SF-36) score and Hospital Anxiety and Depression Scale (HADS) score. All outcomes were assessed at Week 0 (baseline), Week 4 (after-treatment) and Week 8 (follow-up).

RESULTS: Between-group comparisons showed significant differences in the changes in NIBUT (Week 4, p = 0.003; Week 8, p = 0.008), TMH (Week 4, p = 0.014; Week 8, p = 0.009), OSDI (Week 4, p = 0.029; Week 8, p = 0.022), CFS score (Week 8, p = 0.036) and SF-36 role-physical score (Week 4, p = 0.010), favouring EAG. Mean changes in SIT, SAI, SRI, corneal sensitivity and HADS scores were statistically equal between the two groups (all p > 0.05). Treatment with electroacupuncture was well-tolerated and showed minimal adverse events.

CONCLUSIONS: Compared with artificial tears, electroacupuncture shows superior efficacy in improving tear film stability and symptoms of DE.

Study Type : Human Study
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