Compulsive activity combined with anterograde amnesia may be associated with the use of zolpidem. - GreenMedInfo Summary

Abstract Title:

Compulsive activity and anterograde amnesia after zolpidem use.

Abstract Source:

Clin Toxicol (Phila). 2007;45(2):179-81. PMID: 17364638

Abstract Author(s):

Ming-Jun Tsai, Yi-Hung Tsai, Yaw-Bin Huang

Article Affiliation:

Institute of Basic Medical Sciences, National Cheng Kung University, Tinan City, Taiwan. [email protected]

Abstract:

BACKGROUND: Zolpidem is a selective GABAAalpha1 receptor modulator used for its hypnotic-sedative properties. Zolpidem has side effects that are similar but not identical to the benzodiazepines. We report the first cases of compulsive activity combined with anterograde amnesia after the use of zolpidem. CASE REPORT: Three women experienced anterograde amnesia and compulsive repetitive behaviors after zolpidem use. These activities consisted of cleaning, shopping, and eating. These behaviors stopped after discontinuation of the zolpidem. CONCLUSION: These reports demonstrate that compulsive activity combined with anterograde amnesia may be associated with the use of zolpidem. Physicians and pharmacists should be aware of this potential side effect.

Article Published Date : Jan 01, 2007
Study Type : Commentary
Additional Links
Diseases : Amnesia: Drug-Induced : CK(36) : AC(22), Compulsive Behavior: Drug-Induced : CK(1) : AC(1), Drug-Induced Toxicity : CK(562) : AC(83)
Problem Substances : Zolpidem (trade name Ambien) : CK(219) : AC(28)
Adverse Pharmacological Actions : Amnesiac : CK(14) : AC(5)

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Key Research Topics

Disease

Drug-Induced Toxicity
Amnesia: Drug-Induced
Compulsive Behavior: Drug-Induced

Toxic Ingredients

Zolpidem (trade name Ambien)

Adverse Pharmacological Actions

Amnesiac

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