Abstract Title:

Concentrates of buttermilk and krill oil improve cognition in aged rats.

Abstract Source:

Prostaglandins Leukot Essent Fatty Acids. 2020 Apr ;155:102077. Epub 2020 Feb 21. PMID: 32145667

Abstract Author(s):

Alba García-Serrano, Joao Tomé-Carneiro, M Carmen Crespo, M Visitación Calvo, Inmaculada Pereda-Pérez, Shishir Baliyan, Emma Burgos-Ramos, Olimpio Montero, Alberto Dávalos, César Venero, Francesco Visioli, Javier Fontecha

Article Affiliation:

Alba García-Serrano


Cognitive decline is one of the hallmarks of aging and can vary from mild cognitive impairment to dementia to Alzheimer's disease. In addition to some lifestyle interventions, there is room for the use of nutraceuticals/functional foods as pharma-nutritional tools to lessen the burden of cognitive decline before it worsens. We previously reported the promising molecular actions of milk fat globule membranes and krill oil concentrates in a rat model of aging. In this study, we concentrated on the activities on cognition, using an array of validated tests. We also performed lipidomic analyses of plasma, erythrocytes, and different brain areas. We report lower emotional memory (contextual fear conditioning) in aged rats supplemented with concentrates of polar lipids from buttermilk or krill oil at doses that approximate human consumption. No other behavioral parameter was significantly influenced by the supplements, calling for further research to confirm or not the purported salubrious activities of polar lipids, namely those rich inω3 long-chain polyunsaturated fatty acids, on cognitive decline.

Study Type : Animal Study

Print Options

Key Research Topics

Sayer Ji
Founder of GreenMedInfo.com

Subscribe to our informative Newsletter & get Nature's Evidence-Based Pharmacy

Our newsletter serves 500,000 with essential news, research & healthy tips, daily.

Download Now

500+ pages of Natural Medicine Alternatives and Information.

This website is for information purposes only. By providing the information contained herein we are not diagnosing, treating, curing, mitigating, or preventing any type of disease or medical condition. Before beginning any type of natural, integrative or conventional treatment regimen, it is advisable to seek the advice of a licensed healthcare professional.

© Copyright 2008-2022 GreenMedInfo.com, Journal Articles copyright of original owners, MeSH copyright NLM.