Abstract Title:

Effects of Thai Musa species on prevention of UVB-induced skin damage in mice.

Abstract Source:

Food Chem Toxicol. 2012 Sep 8 ;50(12):4292-4301. Epub 2012 Sep 8. PMID: 22986089

Abstract Author(s):

Jarupa Viyoch, Khuanrudee Mahingsa, Kornkanok Ingkaninan

Article Affiliation:

Department of Pharmaceutical Technology, Faculty of Pharmaceutical Sciences and Center of Excellence for Innovation in Chemistry, Naresuan University, Phitsanulok 65000, Thailand. Electronic address: [email protected].

Abstract:

The effects of oral administration of Musa sapientum and Musa suerier on prevention of UVB induced skin damages were investigated in male ICR mice. Animals were orally administered 50mg/day ascorbic acid, or M. sapientum or M. suerier's fruit pulps at dose of 0.5, 1 or 1.5mg/g body weight/day for 12weeks. Concurrently, the shaved backs of animals were irradiated with UVB for 12weeks. The intensity of irradiation was progressively increased, from 54mJ/cm(2) per exposure at week 1-126mJ/cm(2) at week 11. A significant decrease (p<0.05) in skin elasticity (from 0.82±0.02 to 0.42±0.09) and total glutathione (from (193.6±18.7 to 152.7±7.8ng/mg protein) as compared with the control group (water-administered UVB-irradiated mice) was observed after 12weeks of UVB exposure. When l-ascorbic acid (0.72±0.01) or 1mg/g body weight/day M. suerier (0.84±0.06) were administered to UVB-irradiated mice, the reduction in skin elasticity was significantly inhibited (p<0.05). Moreover, the significant increase (p<0.05) in level of total glutathione was found in these groups (220.8±13.3ng/mg protein for l-ascorbic acid and 224.9±20.1ng/mg protein for M. suerier). These findings suggest the potential effect of daily consumption of M. suerier on prevention of skin damage from repeated UVB exposure.

Study Type : Animal Study

Print Options


Key Research Topics

This website is for information purposes only. By providing the information contained herein we are not diagnosing, treating, curing, mitigating, or preventing any type of disease or medical condition. Before beginning any type of natural, integrative or conventional treatment regimen, it is advisable to seek the advice of a licensed healthcare professional.

© Copyright 2008-2024 GreenMedInfo.com, Journal Articles copyright of original owners, MeSH copyright NLM.