n/a
Article Publish Status: FREE
Abstract Title:

Curcumin, but not its degradation products, in combination with silibinin is primarily responsible for the inhibition of colon cancer cell proliferation.

Abstract Source:

MicroPubl Biol. 2022 ;2022. Epub 2022 Jul 28. PMID: 35966396

Abstract Author(s):

Alhan Sayyed, Rita Heuertz, Uthayashanker R Ezekiel

Article Affiliation:

Alhan Sayyed

Abstract:

Colorectal cancer (CRC) is the third leading cause of cancer death globally and the most-commonly diagnosed cancer in men and women in the United States. We have previously shown that the phytochemicals curcumin, derived from turmeric, and silibinin from milk thistle exhibit synergistically enhanced anticancer activity against colorectal cancer cells. In the present study, the combination of curcumin, a major component of turmeric, and its degraded products trans-ferulic acid, ferulic aldehyde, and vanillin in combination with silibinin were assessed for their action against cancer cell proliferation. Our results indicate that only curcumin plus silibinin has significant antiproliferative effects on colon cancer cells.

Study Type : In Vitro Study

Print Options


Key Research Topics

This website is for information purposes only. By providing the information contained herein we are not diagnosing, treating, curing, mitigating, or preventing any type of disease or medical condition. Before beginning any type of natural, integrative or conventional treatment regimen, it is advisable to seek the advice of a licensed healthcare professional.

© Copyright 2008-2024 GreenMedInfo.com, Journal Articles copyright of original owners, MeSH copyright NLM.