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Abstract Title:

Curcumin nanoformulations for antimicrobial and wound healing purposes.

Abstract Source:

Phytother Res. 2021 Feb 15. Epub 2021 Feb 15. PMID: 33587320

Abstract Author(s):

Bahare Salehi, Célia F Rodrigues, Gregorio Peron, Stefano Dall'Acqua, Javad Sharifi-Rad, Lubna Azmi, Ila Shukla, Uttam Singh Baghel, Abhay Prakash Mishra, Ahmed M Elissawy, Abdel Nasser Singab, Raffaele Pezzani, Marco Redaelli, Jayanta Kumar Patra, Chidambaram Kulandaisamy Venil, Gitishree Das, Deeksha Singh, Priyanka Kriplani, Alessandro Venditti, Patrick Valere Tsouh Fokou, Marcello Iriti, Ryszard Amarowicz, Miquel Martorell, Natália Cruz-Martins

Article Affiliation:

Bahare Salehi

Abstract:

The development and spread of resistance to antimicrobial drugs is hampering the management of microbial infectious and wound healing processes. Curcumin is the most active and effective constituent of Curcuma longa L., also known as turmeric, and has a very long and strong history of medicinal value for human health and skincare. Curcumin has been proposed as strong antimicrobial potentialities and many attempts have been made to determine its ability to conjointly control bacterial growth and promote wound healing. However, low aqueous solubility, poor tissue absorption and short plasma half-life due its rapid metabolism needs to be solved for made curcumin formulations as suitable treatment for wound healing. New curcumin nanoformulations have been designed to solve the low bioavailability problem of curcumin. Thus, in the present review, the therapeutic applications of curcumin nanoformulations for antimicrobial and wound healing purposes is described.

Study Type : Review
Additional Links
Pharmacological Actions : Antimicrobial : CK(776) : AC(352)

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