Abstract Title:

Comparative protective action of curcumin, memantine and diclofenac against scopolamine-induced memory dysfunction.

Abstract Source:

Fitoterapia. 2011 Jan 26. Epub 2011 Jan 26. PMID: 21277954

Abstract Author(s):

Elham H A Ali, Nadia M S Arafa

Article Affiliation:

Zoology Department, Women College, for Arts, Science and Education, Ain Shams University, Cairo, Egypt.


The comparative preventive effect of curcumin, memantine, and diclofenac on scopolamine-induced memory dysfunction was investigated in a controlled study. A group of male and female rats was treated with one of these compounds for 15days, after which a single dosage of scopolamine was administered. The preventive activity of curcumin on memory dysfunction was higher than that of diclofenac or memantine, that was, however, administered at lower dosages. Gender differences were observed.

Study Type : Animal Study

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