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Article Publish Status: FREE
Abstract Title:

Cutaneous Squamous Cell Carcinoma and Lichen Simplex Chronicus Successfully Treated with Topical Cannabinoid Oil: A Case Report and Summary of Cannabinoids in Dermatology.

Abstract Source:

Cureus. 2022 Apr ;14(4):e23850. Epub 2022 Apr 5. PMID: 35530920

Abstract Author(s):

Jennifer Laborada, Philip R Cohen

Article Affiliation:

Jennifer Laborada

Abstract:

Cannabidiol is a member of the cannabinoids, consisting of a diverse class of compounds derived from. There are three types of cannabinoids based on origin: endocannabinoids (endogenous), phytocannabinoids (plant-derived), and synthetic cannabinoids (synthesized). The endocannabinoid system plays a key role in skin homeostasis, such as proliferation, differentiation, and inflammatory signaling. A 64-year-old woman with a history of multiple squamous cell carcinomas who presented with skin lesions on her bilateral dorsal hands is reported. Her skin biopsies showed lichen simplex chronicus on her left hand and squamous cell carcinoma on her right hand; both lesions resolved with topical application of 20% cannabidiol. Cutaneous adverse events associated with cannabinoid use and potential therapeutic uses of cannabinoids in inflammatory skin diseases and skin cancer are also summarized.

Study Type : Human: Case Report

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Sayer Ji
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