Abstract Title:

Daily intake of 100 mg ascorbic acid as urinary tract infection prophylactic agent during pregnancy.

Abstract Source:

J Ethnopharmacol. 2009 Mar 18;122(2):320-6. Epub 2008 Dec 27. PMID: 17611821

Abstract Author(s):

Gonzalo Javier Ochoa-Brust, Alma Rosa Fernández, Gerson Jesús Villanueva-Ruiz, Raymundo Velasco, Benjamín Trujillo-Hernández, Clemente Vásquez

Article Affiliation:

Centro Universitario de Investigaciones Biomédicas y Facultad de Enfermería, Universidad de Colima, Colima, México.


OBJECTIVE: To evaluate the role a daily intake of 100 mg of ascorbic acid plays in urinary infection prophylaxis during pregnancy.

METHODS AND MATERIALS: A single-blind clinical trial was carried out on pregnant women randomly assigned to the following treatment groups - Group A: oral treatment with ferrous sulphate (200 mg per day), folic acid (5 mg per day) and ascorbic acid (100 mg per day) for 3 months, and Group B: oral treatment with ferrous sulphate (200 mg per day) and folic acid (5 mg per day) for 3 months. All patients were clinically evaluated, and a urine culture was carried out each month for a period of 3 months. The chi(2) and odds ratio were used to compare effects with and without ascorbic acid, and statistical significance was considered at p<0.05.

RESULTS: Global frequency of urinary infections was 25%. The presence of urinary infections in Group A (12.7%) was significantly lower than in Group B (29.1%), (p=0.03, OR =0.35, CI 95% =0.13-0.91).

CONCLUSIONS: Daily intake of 100 mg of ascorbic acid played an important role in the reduction of urinary infections, improving the health level of the gestating women. We recommend additional vitamin C intake for pregnant women in populations which have a high incidence of bacteriuria and urinary infections.

Study Type : Human Study

Print Options

This website is for information purposes only. By providing the information contained herein we are not diagnosing, treating, curing, mitigating, or preventing any type of disease or medical condition. Before beginning any type of natural, integrative or conventional treatment regimen, it is advisable to seek the advice of a licensed healthcare professional.

© Copyright 2008-2024 GreenMedInfo.com, Journal Articles copyright of original owners, MeSH copyright NLM.