Article Publish Status: FREE
Abstract Title:

In vitro Evaluation of the Antiviral Activity of an Extract of Date Palm (Phoenix dactylifera L.) Pits on a Pseudomonas Phage.

Abstract Source:

Evid Based Complement Alternat Med. 2010 Mar ;7(1):57-62. Epub 2007 Oct 27. PMID: 18955267

Abstract Author(s):

Sabah A A Jassim, Mazen A Naji

Article Affiliation:

Sabah A A Jassim


A crude acetone extract of the pit of date palm (Phoenix dactylifera L.) was prepared and its antiviral activity evaluated against lytic Pseudomonas phage ATCC 14209-B1, using Pseudomonas aeruginosa ATCC 25668 as the host cell. The antiviral activity of date pits was found to be mediated by binding to the phage, with minimum inhibitory concentration (MIC) of<10μg ml(-1). The decimal reduction time (D-values), the concentration exponent (η) and the phage inactivation kinetics were determined. The date pit extracts show a strong ability to inhibit the infectivity of Pseudomonas phage ATCC 14209-B1 and completely prevented bacterial lysis, which it is hoped will promote research into its potential as a novel antiviral agent against pathogenic human viruses.

Study Type : Viral
Additional Links
Pharmacological Actions : Antiviral Agents : CK(1957) : AC(1034)

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