Abstract Title:

Colored lenses suppress blue light-emitting diode light-induced damage in photoreceptor-derived cells.

Abstract Source:

J Biomed Opt. 2016 Mar ;21(3):35004. PMID: 27008925

Abstract Author(s):

Kaho Hiromoto, Yoshiki Kuse, Kazuhiro Tsuruma, Nobuyuki Tadokoro, Nobuyuki Kaneko, Masamitsu Shimazawa, Hideaki Hara

Article Affiliation:

Kaho Hiromoto


Blue light-emitting diodes (LEDs) in liquid crystal displays emit high levels of blue light, exposure to which is harmful to the retina. Here, we investigated the protective effects of colored lenses in blue LED light-induced damage to 661W photoreceptor-derived cells. We used eight kinds of colored lenses and one lens that reflects blue light. Moreover, we evaluated the relationship between the protective effects of the lens and the transmittance of lens at 464 nm. Lenses of six colors, except for the SY, PN, and reflective coating lenses, strongly decreased the reduction in cell damage induced by blue LED light exposure. The deep yellow lens showed the most protective effect from all the lenses, but the reflective coating lens and pink lens did not show any effects on photoreceptor-derived cell damage. Moreover, these results were correlated with the lens transmittance of blue LED light (464 nm). These results suggest that lenses of various colors, especially deep yellow lenses, may protect retinal photoreceptor cells from blue LED light in proportion to the transmittance for the wavelength of blue LED and the suppression of reactive oxygen species production and cell damage.

Study Type : In Vitro Study

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