Dibenzofurans from Crataegus oresbia and their lipid-lowering activity. - GreenMedInfo Summary
Dibenzofurans fromand their lipid-lowering activity.
Nat Prod Res. 2022 Feb 6:1-7. Epub 2022 Feb 6. PMID: 35129009
Ying Wang
Three new dibenzofurans, 2-hydroxy-3,4-dimethoxydibenzofuran (), 2,8-dihydroxy-3,4,9-trimethoxydibenzofuran () and 2-hydroxy-3,4,6,8-tetramethoxydibenzofuran (), together with three known dibenzofurans 1-hydroxy-2,3,4-trimethoxydibenzofuran (), 2-hydroxy-3,4,6-trimethoxydibenzofuran () and 1,6-dihydroxy-2,3,4-trimethoxydibenzofuran (), were isolated from the twigs and leaves of. Their structures were identified by the comprehensive analyses of the physicochemical properties and spectroscopic data (NMR and HR-ESI-MS). Compoundsshowed significantlipid-lowering activities, especially compoundwas stronger than simvastatin.