Article Publish Status: FREE
Abstract Title:

Dietary Selenium Intakes and Musculoskeletal Function in Very Old Adults: Analysis of the Newcastle 85+ Study.

Abstract Source:

Nutrients. 2020 Jul 12 ;12(7). Epub 2020 Jul 12. PMID: 32664662

Abstract Author(s):

Giorgia Perri, Nuno Mendonça, Carol Jagger, Jennifer Walsh, Richard Eastell, John C Mathers, Tom R Hill

Article Affiliation:

Giorgia Perri


: Selenium is a trace element essential for health. Severe selenium deficiencies are associated with poor musculoskeletal (MSK) function. However, the effects of moderate deficiency on MSK function, especially in older adults, is unclear.: To determine the associations between selenium intake and MSK function in very old adults.: Selenium intake at baseline and, hand-grip strength (HGS) and timed-up-and-go (TUG) at four phases over 5 years, were available in 791 participants in the Newcastle 85+ Study, a community-based, longitudinal cohort of≥85 year old individuals. We investigated relationships between selenium intake and HGS and TUG in cross-sectional analyses at baseline using multivariate analyses and, prospectively using linear mixed models to explore HGS and TUG changes over 5 years in association with baseline selenium intake.: At baseline, 53% of participants had selenium intakes that were classified as low. These individuals had 2.80 kg lower HGS and were 2.30 s slower performing the TUG, cross-sectionally. In multivariate, baseline analyses, selenium intake had no significant impact on HGS or TUG. Selenium intake had no significant effect on MSK function, prospectively.: Low selenium intake is common among very old adults and, in cross-sectional analyses, is associated with poorer MSK function.

Study Type : Human Study

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