Diosmin has a significant clinical effect on middle-sized vein-related trophic ulcers. - GreenMedInfo Summary

Abstract Title:

Micronized diosmin (Detralex) for vein-related trophic ulcers: European experience.

Abstract Source:

Angiol Sosud Khir. 2006;12(3):53-60. PMID: 17641615

Abstract Author(s):

V S Savel'ev, A V Pokrovskiĭ, S V Sapelkin, V Iu Bogachev, L I Bogdanets, I A Zolotukhin

Abstract:

The paper presents a meta-analysis of 5 large European studies (N - 723) on the micronized diosmin administration to patients with venous trophic ulcers (CEAP class VI). With the use of evidence-based approach, it was shown that micronized diosmin has a statistically significant clinical effect on middle-sized trophic ulcers (5 - 10 cm(2)) that persisted for 6 - 12 months. The study concludes that polyvalent venotonics are an appropriate and valuable addition to complex therapy of complicated chronic venous insufficiency..

Article Published Date : Jan 01, 2006
Study Type : Review
Additional Links
Substances : Diosmin : CK(303) : AC(113)
Diseases : Chronic Venous Insufficency : CK(74) : AC(13), Venous Ulcer : CK(80) : AC(13)

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Key Research Topics

Disease

Chronic Venous Insufficency
Venous Ulcer

Substance

Diosmin

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