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Abstract Title:

Dose-dependent Effects of Cacao Polyphenol Intake on Lipid Metabolism in Rats.

Abstract Source:

Plant Foods Hum Nutr. 2021 Jun ;76(2):254-255. Epub 2021 Apr 8. PMID: 33830369

Abstract Author(s):

Yuka Aono, Takanobu Kaido, Nagisa Kita, Kaho Sugiyama, Maho Sumikawa, Shizuka Nakayama, Yukiko Fukushima

Article Affiliation:

Yuka Aono

Abstract:

Cacao polyphenols (CPs) are known to suppress the oxidation of low-density lipoprotein and cholesterol absorption. Herein, we examined the impact of CP on the lipid metabolism in rats fed CP-rich chocolate, by analyzing liver weight and histology, via hematoxylin-eosin staining. The high-CP group had significantly lighter livers than the CP-free group. Histologically, the high-CP group showed significantly lower liver fat accumulation than the CP-free group. These results suggest that CPs prevent liver fat accumulation, being potentially useful against obesity and related diseases.

Study Type : Animal Study

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