Abstract Title:

Naloxone antagonises effect of alpha-gliadin on leucocyte migration in patients with coeliac disease.

Abstract Source:

Lancet. 1985 Jul 27;2(8448):184-5. PMID: 2862373

Abstract Author(s):

K Horváth, L Gráf, E Walcz, H Bodánszky, D Schuler


The effect of naloxone on inhibition of leucocyte migration by alpha-gliadin was examined in 24 patients with coeliac disease. In all cases in which alpha-gliadin inhibited leucocyte migration, naloxone blocked this inhibitory effect, which suggests that the effect of gliadin on lymphocytes from patients with coeliac disease may be mediated through opioid-like receptors.

Study Type : Commentary
Additional Links
Problem Substances : Gliadin : CK(821) : AC(118)

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