The effect of gliadin on lymphocytes from patients with celiac disease may be mediated through opioid-like receptors. - GreenMedInfo Summary
Naloxone antagonises effect of alpha-gliadin on leucocyte migration in patients with coeliac disease.
Lancet. 1985 Jul 27;2(8448):184-5. PMID: 2862373
The effect of naloxone on inhibition of leucocyte migration by alpha-gliadin was examined in 24 patients with coeliac disease. In all cases in which alpha-gliadin inhibited leucocyte migration, naloxone blocked this inhibitory effect, which suggests that the effect of gliadin on lymphocytes from patients with coeliac disease may be mediated through opioid-like receptors.