Article Publish Status: FREE
Abstract Title:

Effect of Prebiotics-Enhanced Probiotics on the Growth of.

Abstract Source:

Int J Microbiol. 2019 ;2019:4623807. Epub 2019 Aug 1. PMID: 31467551

Abstract Author(s):

Santichai Nunpan, Chatrudee Suwannachart, Kornchanok Wayakanon

Article Affiliation:

Santichai Nunpan


predominantly creates an acidic environment in an oral cavity. This results in dental demineralization and carious lesions. The probiotics are beneficial microorganisms that modulate the bacterial balance in the digestive system. Prebiotics are defined as nondigestible oligosaccharides that are utilized for the selective stimulation of the beneficial microorganisms. The objective of this study was to evaluate the efficacy of the prebiotics, galactooligosaccharides (GOS) and fructooligosaccharides (FOS), for enhancing the probioticATCC 4356, for inhibiting(A32-2) for the prevention of dental caries. The growth rate of thesignificantly decreased when cocultured within the GOS-supplemented medium at 3%, 4%, and 5%. In the FOS-supplemented medium, the growth rate ofsignificantly decreased in all concentrations when cocultured with. There was no significant difference in the growth rate ofin all concentrations of either GOS or FOS. It can be concluded that the growth rate ofwas significantly retarded when cocultured withand the proper concentration of prebiotics. These prebiotics have potential for a clinical application to activate the function of the naturally intraoralto inhibit.

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