n/a
Abstract Title:

Effect ofsupplementation on Exercise-Induced Oxidative Stress and Delayed Onset Muscle Soreness Markers: A Pilot Study.

Abstract Source:

J Diet Suppl. 2022 Sep 8:1-21. Epub 2022 Sep 8. PMID: 36073362

Abstract Author(s):

Leila Ataei, Christoforos D Giannaki, Christos Petrou, George Aphamis

Article Affiliation:

Leila Ataei

Abstract:

L. contains compounds with antioxidant and anti-inflammatory properties, but its effects on exercise-induced oxidative stress and inflammatory responses are unclear. The aim of this study was to examine whetherL. supplementation can attenuate oxidative stress and inflammatory responses to acute aerobic exercise and improve DOMS. In a randomized, double-blind, crossover design study, thirteen healthy men received either a daily supplement ofL. or a placebo for 4 weeks (2-week wash-out period between trials). Before and after the supplementation periods, participants performed an exercise test to exhaustion (75% VOmax). DOMS, thigh girth, and knee joint range of motion (KJRM) were assessed before and after the exercise (2, 24, and 48 h). Blood samples were analyzed for reduced (GSH) and oxidized (GSSG) glutathione, GSH/GSSG ratio, protein carbonyls, total antioxidant capacity, creatine kinase activity, white blood cell count, and TBARS. Acute exercise to exhaustion induced inflammatory responses and changed the blood redox status in both Tribulus and Placebo groups ( < 0.050).L. improved GSH fall ( = 0.005), GSSG rise ( = 0.001) and maintained a higher level of GSH/GSSG ratio at the 2 h point ( = 0.034). TBARS were lowered, protein carbonyls, creatine kinase activity, and white blood cell count elevation diminished significantly ( < 0.050).L. administration did not affect DOMS, thigh girth, or KJRM ( > 0.050). 4-weeks ofL. supplementation effectively attenuates oxidative stress responses but cannot improve DOMS.

Study Type : Human Study

Print Options


Key Research Topics

This website is for information purposes only. By providing the information contained herein we are not diagnosing, treating, curing, mitigating, or preventing any type of disease or medical condition. Before beginning any type of natural, integrative or conventional treatment regimen, it is advisable to seek the advice of a licensed healthcare professional.

© Copyright 2008-2024 GreenMedInfo.com, Journal Articles copyright of original owners, MeSH copyright NLM.