Article Publish Status: FREE
Abstract Title:

Electro-acupuncture regulates glucose metabolism in chronic stress model rats.

Abstract Source:

Sci Rep. 2020 Jul 9 ;10(1):11281. Epub 2020 Jul 9. PMID: 32647204

Abstract Author(s):

Fu-Qiang Ma, Chan-Juan Sun, Jun-Jie Wei, Ya-Dong Wang, Jia-Cheng Shen, Jin-Jian Chang

Article Affiliation:

Fu-Qiang Ma


Studies have shown that acupuncture is very effective in treating chronic stress depression. However, little is known about the therapeutic mechanism of electro-acupuncture. Metabolomics, on the other hand, is a technology that determines the metabolic changes of organisms caused by various interventions as a whole and is related to the overall effect of electro-acupuncture (EA).HNMR, serum sample analysis, and histopathology and molecular biology analysis were used to evaluate the effects of EA. The results show that electro-acupuncture points can regulate the heat pain threshold of chronic stress model rats and change the morphology of adrenal cortex cells Structure, and regulate the contents of corticotropin-releasing hormone, Corticosterone (CORT), glucose, alanine and valine in the samples. These findings help to clarify the therapeutic mechanism of electro-acupuncture on heterologous chronic stress model rats. The effect of electro-acupuncture on improving chronic stress is likely to be achieved by regulating glucose metabolism, which can provide a reference for clinical acupuncture treatment of chronic stress depression.

Study Type : Animal Study

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Sayer Ji
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