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Article Publish Status: FREE
Abstract Title:

Enhanced Resorption of Liposomal Packed Vitamin C Monitored by Ultrasound.

Abstract Source:

J Clin Med. 2020 May 26 ;9(6). Epub 2020 May 26. PMID: 32466592

Abstract Author(s):

Lukas Prantl, Andreas Eigenberger, Sebastian Gehmert, Silke Haerteis, Thiha Aung, Reinhard Rachel, Ernst Michael Jung, Oliver Felthaus

Article Affiliation:

Lukas Prantl

Abstract:

Vitamin C is an essential nutrient for humans and is involved in a plethora of health-related functions. Several studies have shown a connection between vitamin C intake and an improved resistance to infections that involves the immune system. However, the body cannot store vitamin C and both the elevated oral intake, and the intravenous application have certain disadvantages. In this study, we wanted to show a new formulation for the liposomal packaging of vitamin C. Using freeze etching electron microscopy, we show the formed liposomes. With a novel approach of post-processing procedures of real-time sonography that combines enhancement effects by contrast-like ultrasound with a transducer, we wanted to demonstrate the elevated intestinal vitamin C resorption on four participants. With the method presented in this study, it is possible to make use of the liposomal packaging of vitamin C with simple household materials and equipment for intake elevation. For the first time, we show the enhanced resorption of ingested liposomes using microbubble enhanced ultrasound imaging.

Study Type : In Vitro Study
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