Evaluation of myocardial damage after electroconvulsive therapy. - GreenMedInfo Summary

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Abstract Title:

Evaluation of Myocardial Damage After Electroconvulsive Therapy: Analyses of High-Sensitive Cardiac Troponin I and N-Terminal pro-B-type Natriuretic Peptide.

Abstract Source:

Pharmacopsychiatry. 2019 Feb ;52(2):92-93. Epub 2018 Jul 2. PMID: 29966142

Abstract Author(s):

Laura Kranaster, Johanna Badstübner, Suna Su Aksay, Jan Malte Bumb, Rayan Suliman, Michael Neumaier, Alexander Sartorius

Article Affiliation:

Laura Kranaster

Abstract:

Electroconvulsive therapy (ECT) is a remarkably safe procedure. However, there might exist a subgroup of patients with an increased risk for cardiovascular events. The cardiac-specific enzymes high-sensitive cardiac troponin I (hscTnI) and N-terminal pro-B-type natriuretic peptide (NT-proBNP) were measured before and after ECT in 23 patients. No relevant increase of hscTnI after ECT was found. Mean NT-proBNP levels were higher after ECT and in three patients a new NT-proBNP elevation after ECT was identified. In conclusion, our small study did not find any evidence for myocardial damage due to ECT by measuring hsTnI, but an increase of NT-proBNP, whose clinical relevance could only be speculated, yet.

Article Published Date : Jan 31, 2019
Study Type : Human Study
Additional Links
Anti Therapeutic Actions : Electroconvulsive Therapy : CK(1608) : AC(228)
Adverse Pharmacological Actions : Cardiotoxic : CK(1303) : AC(237)

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Key Research Topics

Adverse Pharmacological Actions

Cardiotoxic

Anti-Therapeutic Action

Electroconvulsive Therapy

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