An extract of Dill had significant antidepressant and analgesic effects compared with the drug references without any adverse effects. - GreenMedInfo Summary

Abstract Title:

Phytochemical Screening, Antidepressant and Analgesic Effects of Aqueous Extract of Anethum graveolens L. From Southeast of Morocco.

Abstract Source:

Am J Ther. 2016 Feb 11. Epub 2016 Feb 11. PMID: 26872137

Abstract Author(s):

Latifa El Mansouri, Dalila Bousta, Amal El Youbi-El Hamsas, Smahane Boukhira, Hassane Akdime

Article Affiliation:

Latifa El Mansouri

Abstract:

This study aims to investigate the antidepressant and analgesic properties of the aqueous extract of Anethum graveolens L. from South of Morocco (Rissani-Errachidia region). Extract of plant is obtained by aqueous decoction and administered to Wistar rats orally. The extract has a significant antidepressant and analgesic effects compared with the drug references (sertraline and tramadol) without any adverse effects. The dose of 250 mg/kg, body weight shows the best antidepressant and analgesic effects than 1 g/kg, body weight. Phytochemical study of the aqueous extract of the plant has to show its highlight in polyphenols, flavonoids, and tannins.

Article Published Date : Feb 10, 2016

Study Type : Animal Study

Additional Links

Substances : Dill : CK(154) : AC(50)

Diseases : Chronic Pain : CK(1018) : AC(212), Depression : CK(6233) : AC(1590)

Pharmacological Actions : Analgesics : CK(3498) : AC(943), Antidepressive Agents : CK(4882) : AC(1328)

Additional Keywords : Plant Extracts : CK(17959) : AC(6472), Superiority of Natural Substances versus Drugs : CK(1644) : AC(387), Tramadol : CK(2) : AC(1)

Problem Substances : Sertraline : CK(10) : AC(8)