Abstract Title:

Extracts and Flavonoids of Passiflora Species as Promising Anti-inflammatory and Antioxidant Substances.

Abstract Source:

Curr Pharm Des. 2020 May 26. Epub 2020 May 26. PMID: 32452323

Abstract Author(s):

Marcin Ożarowski, Tomasz M Karpiński

Article Affiliation:

Marcin Ożarowski


There is increasing interest in evaluating anti-inflammatory activities of plant substances such as extracts and flavonoid rich fractions. A promising source of new medicinal drugs may be species from the Passifloraceae family. The most interesting group of principal chemical compounds in Passiflora species are polyphenolic compounds, including flavonoids due to their antioxidant activity demonstrated in various studies (quercetin, rutin, apigenin, luteolin, chrysin, and Cglycosylflavones i.e., vitexin, isovitexin, orientin, isoorientin). However, each extracts from Passiflora spp. as multi-component mixtures should be estimated for chemical composition (in the standardization process) and their activity using in vitro and in vivo tests. The current standard for drug discovery and development from plants indicates that only collective assessment allows estimating plant substances by definition of the origin of raw materials and their quality, methods of extractions, and metabolite profiles. Increasingly, due to complex phytochemical procedures to obtain extracts, individual flavonoid compounds are also tested for anti-inflammatory action. However, it should be emphasized that various sources of potential new drugs from plant origin are not mutually exclusive, but are complementary. A review of bibliographic data includes the following information about Passiflora species, such as distribution, classification, phytochemical compounds, antiinflammatory activity of extracts, anti-inflammatory activity of flavonoids, and antioxidant potential. The review allows concluded that extracts and flavonoids (mainly quercetin, apigenin, and vitexin) from Passiflora spp. can be a valuable source of anti-inflammatory and anti-oxidative medications for the prevention and treatment of many diseases, which occur with complex inflammatory processes.

Print Options

Sayer Ji
Founder of GreenMedInfo.com

Subscribe to our informative Newsletter & get Nature's Evidence-Based Pharmacy

Our newsletter serves 500,000 with essential news, research & healthy tips, daily.

Download Now

500+ pages of Natural Medicine Alternatives and Information.

This website is for information purposes only. By providing the information contained herein we are not diagnosing, treating, curing, mitigating, or preventing any type of disease or medical condition. Before beginning any type of natural, integrative or conventional treatment regimen, it is advisable to seek the advice of a licensed healthcare professional.

© Copyright 2008-2022 GreenMedInfo.com, Journal Articles copyright of original owners, MeSH copyright NLM.