Four patients treated with CBD had prompt and substantial reduction in the frequency of REM sleep behaviour disorder related events without side effects. - GreenMedInfo Summary

Abstract Title:

Cannabidiol can improve complex sleep-related behaviours associated with rapid eye movement sleep behaviour disorder in Parkinson's disease patients: a case series.

Abstract Source:

J Clin Pharm Ther. 2014 Oct ;39(5):564-6. Epub 2014 May 21. PMID: 24845114

Abstract Author(s):

M H N Chagas, A L Eckeli, A W Zuardi, M A Pena-Pereira, M A Sobreira-Neto, E T Sobreira, M R Camilo, M M Bergamaschi, C H Schenck, J E C Hallak, V Tumas, J A S Crippa

Article Affiliation:

M H N Chagas

Abstract:

WHAT IS KNOWN AND OBJECTIVE: Cannabidiol (CBD) is the main non-psychotropic component of the Cannabis sativa plant. REM sleep behaviour disorder (RBD) is a parasomnia characterized by the loss of muscle atonia during REM sleep associated with nightmares and active behaviour during dreaming. We have described the effects of CBD in RBD symptoms in patients with Parkinson's disease.

CASES SUMMARY: Four patients treated with CBD had prompt and substantial reduction in the frequency of RBD-related events without side effects.

WHAT IS NEW AND CONCLUSION: This case series indicates that CBD is able to control the symptoms of RBD.

Article Published Date : Sep 30, 2014
Study Type : Human: Case Report
Additional Links
Substances : Cannabidiol : CK(3371) : AC(1007), Cannabis : CK(4688) : AC(1192)
Diseases : Sleep Disorders : CK(1979) : AC(267)
Additional Keywords : Phytotherapy : CK(3979) : AC(1021), Significant Treatment Outcome : CK(4297) : AC(505)

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Key Research Topics

Disease

Sleep Disorders

Substance

Cannabis
Cannabidiol

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