Article Publish Status: FREE
Abstract Title:

Ionone Derivatives from the Mycelium of Phellinus linteus and the Inhibitory Effect on Activated Rat Hepatic Stellate Cells.

Abstract Source:

Int J Mol Sci. 2016 ;17(5). Epub 2016 May 6. PMID: 27164091

Abstract Author(s):

Shiow-Chyn Huang, Ping-Chung Kuo, Hsin-Yi Hung, Tai-Long Pan, Fu-An Chen, Tian-Shung Wu

Article Affiliation:

Shiow-Chyn Huang


Three newγ-ionylideneacetic acid derivatives, phellinulins A-C (1-3), were characterized from the mycelium extract of Phellinus linteus. The chemical structures were established based on the spectroscopic analysis. In addition, phellinulin A (1) was subjected to the examination of effects on activated rat hepatic stellate cells and exhibited significant inhibition of hepatic fibrosis.

Study Type : In Vitro Study

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