Geum japonicum contains a compound with anti-HIV activity. - GreenMedInfo Summary

Abstract Title:

A new anti-HIV triterpene from Geum japonicum.

Abstract Source:

Chem Pharm Bull (Tokyo). 2000 Sep;48(9):1367-9. PMID: 10993241

Abstract Author(s):

H X Xu, D S Ming, H Dong, P P But

Article Affiliation:

Department of Biology and Institute of Chinese Medicine, The Chinese University of Hong Kong, Shatin, NT.

Abstract:

Geumonoid (1), a new triterpene, was isolated from Geum japonicum. Its structure was elucidated on the basis of 1D, 2D NMR and MS spectroscopic analysis. Compound 1 showed inhibitory activity against HIV-1 protease.

Article Published Date : Sep 01, 2000
Study Type : In Vitro Study
Additional Links
Substances : Geum japonicum : CK(24) : AC(16)
Diseases : HIV Infections : CK(1178) : AC(396)
Pharmacological Actions : Anti-HIV Agents : CK(155) : AC(96), HIV Protease Inhibitors : CK(33) : AC(21)

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Key Research Topics

Disease

HIV Infections

Pharmacological Actions

Anti-HIV Agents
HIV Protease Inhibitors

Substance

Geum japonicum

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