Ginger contains compounds which inhibit rhinoviral activity. - GreenMedInfo Summary

Abstract Title:

Isolation of antirhinoviral sesquiterpenes from ginger (Zingiber officinale).

Abstract Source:

Brain Res. 2004 Sep 10;1020(1-2):1-11. PMID: 8064299

Abstract Author(s):

C V Denyer, P Jackson, D M Loakes, M R Ellis, D A Young

Abstract:

The dried rhizomes of Indonesian ginger, Zingiber officinale, were investigated for antirhinoviral activity in the plaque reduction test. Fractionation by solvent extraction, solvent partition, and repeated chromatography guided by bioassay, allowed the isolation of several sesquiterpenes with antirhinoviral activity. The most active of these was beta-sesquiphellandrene [2] with an IC50 of 0.44 microM vs. rhinovirus IB in vitro.

Article Published Date : Sep 10, 2004
Study Type : In Vitro Study
Additional Links
Substances : Ginger : CK(1589) : AC(476)
Diseases : Rhinovirus Infection : CK(97) : AC(39)
Pharmacological Actions : Antiviral Agents : CK(2973) : AC(1668)

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Key Research Topics

Substance

Ginger

Pharmacological Actions

Antiviral Agents

Disease

Rhinovirus Infection

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