Abstract Title:

The anti-ulcer effect in rats of ginger constituents.

Abstract Source:

J Ethnopharmacol. 1988 Jul-Aug;23(2-3):299-304. PMID: 3193792

Abstract Author(s):

J Yamahara, M Mochizuki, H Q Rong, H Matsuda, H Fujimura


The effects of ginger, a pungent stomachic natural medicine, on HCl/ethanol-induced gastric lesions in rats, were examined. The orally administered acetone extract at 1000 mg/kg and zingiberene, the main terpenoid from acetone extract, at 100 mg/kg significantly inhibited gastric lesions by 97.5 and 53.6%, respectively. 6-Gingerol, the pungent principle, at 100 mg/kg significantly inhibited gastric lesions by 54.5%. These results suggest that zingiberene, the terpenoid and 6-gingerol are important constituents in stomachic medications containing ginger.

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