Abstract Title:

Ginger (Zingiber officinale Roscoe) as a nutraceutical: Focus on the metabolic, analgesic, and antiinflammatory effects.

Abstract Source:

Phytother Res. 2020 Dec 5. Epub 2020 Dec 5. PMID: 33278054

Abstract Author(s):

Ester Pagano, Eliana B Souto, Alessandra Durazzo, Javad Sharifi-Rad, Massimo Lucarini, Selma B Souto, Bahare Salehi, Wissam Zam, Vittorino Montanaro, Giuseppe Lucariello, Angelo A Izzo, Antonello Santini, Barbara Romano

Article Affiliation:

Ester Pagano


Ginger (from the rizhome of Zingiber officinale Roscoe) has been widely used in ethnomedicine for the cure of several ailments. Main active ingredients include phenolic compounds named gingerols. In modern phytotherapy, ginger preparations are predominantly used to counteract nausea and vomiting in pregnant women. However, a number of other pharmacological actions of potential therapeutic interest, which might broaden the spectrum of its clinical use, have been reported. This focused review aims at giving a shot on the antinflammatory, analgesic, and metabolic actions of Zingiber officinale preparations, with a discussion on the clinical applications in knee osteoarthritis, dysmenorrhea, type-2 diabetes, hyperlipidemia, overweight, and obesity.

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